Name: _____________________________________    Date: ____________

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Student Worksheet: Phagocytosis & Bacterial Pathogens

Instructions:

• Print out a paper copy of this worksheet.
• Explore the web-based flash animation “Phagocytosis & Bacterial Pathogens”, by Thomas Terry.
  URL = http://www.sp.uconn.edu/~terry/Common/phagocytosis.html
• As you explore, look for answers to the questions, and fill in the worksheet
• Return the completed worksheet to your instructor as directed.

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Questions:

1. Where are macrophages found in the human body?
   
   
2. What cells carry out phagocytosis?
   
   
3. What is a phagosome?
   
   
4. What is in a lysosome?
   
   
5. How is a phagolysosome formed?
   
   
6. What happens during an “oxygen burst”?
   
   
7. What are the end products of phagocytosis?
   
   
8. What happens to the products of phagocytosis?
   
   
9. What bacterium causes plague?
   
   
10. Is plague infection an intracellular or extracellular process?
    
    
11. What is the role of Type III secretory apparatus during plague infection?
    
    
12. What are YOPs?
    
    
13. Identify the mode of action of at least one YOP.
    
    
14. What is a common symptom of plague infection?
    
    
15. What bacterium causes tuberculosis (TB)?
    
    
16. Is TB infection an intracellular or extracellular process?
    
    
17. How many people worldwide are estimated to be infected with the TB pathogen?
    
    
18. How many of these people will actually develop some clinical symptoms of TB?
    
    
19. What happens to the TB bacteria in those people who don’t have any clinical symptoms?
    
    
20. How many people die each year as a result of TB?
    
    
21. What prevents TB bacteria from being killed by phagocytosis?
    
    
22. What organ(s) in the human body can be infected with TB?